Lionel Messi had to wait 12 years and endure a goal drought of eight games against Chelsea but he finally broke his duck in Tuesday's 1-1 Champions League last 16, first leg draw.
Here are five talking points from the weekend in La Liga.
La Liga leaders Barcelona drew 0-0 at Huesca on Saturday and are nine points clear of second-placed Atletico Madrid, who cut the gap by beating Celta Vigo 2-0.
Real Madrid's faltering title defence continued as they were held to a thrilling 2-2 draw at Celta Vigo on Sunday which saw them fall 16 points behind runaway leaders Barcelona, who beat Levante 3-0 to stay nine points clear at the top of La Liga.
Sevilla became surprise Liga leaders on Sunday after beating visiting Celta Viga 2-1 while champions Barcelona drew 1-1 at Valencia thanks to another Lionel Messi strike but are still without a victory in their last four league games.
La Liga champions Barcelona fell to their first opening day defeat of the season in 11 years when they were beaten 1-0 at Athletic Bilbao thanks to a sensational late overhead kick from veteran striker Aritz Aduriz.
Included in Barcelona squad to face Dortmund
Barcelona snatched a late 2-1 win at Getafe with Paulinho's strike sending them seven points clear of arch-rivals Real Madrid at the top of La Liga.
Champions Barcelona moved five points clear at the top of La Liga with a 2-1 win at Getafe, while Real Madrid fell to a 2-0 defeat by Real Sociedad.
Lionel Messi scored his 12th league goal of the season but Barcelona had to rely on exceptional saves from Marc-Andre ter Stegen as they rode their luck to win 2-0 at Athletic Bilbao on Saturday and stay four points clear at the top of La Liga.
Real Madrid talisman Cristiano Ronaldo and Barcelona striker Luis Suarez took centre stage on Saturday in bailing their teams out with late strikes to silence their critics following slow starts to the season.
An insatiable Lionel Messi hit a hat-trick as Barcelona hammered Espanyol 5-0 in a local derby on Saturday to make it three wins from three and take full advantage after Liga champions Real Madrid were held to a 1-1 draw at home to Levante.
La Liga leaders Barcelona hit two goals in the final three minutes to earn a 3-2 win at Rayo Vallecano
Leaders Barcelona and Real Madrid were held to draws while Sevilla made up ground on the top two and Alaves slipped after a promising start. Here are five talking points from the weekend's La Liga action.
Real Madrid ended their long wait for a La Liga victory by beating Real Valladolid 2-0 on Saturday with two late goals in interim coach Santiago Solari's first home game in charge of the struggling European champions.
Images from the football matches played across Europe on Sunday.
The win increased Zinedine Zidane's side's advantage at the top of the standings to six points
Barcelona captain Andres Iniesta lifted a ninth Liga title after his side beat Real Sociedad 1-0 on Sunday in an emotional final game for the midfielder at the Nou Camp while Fernando Torres scored twice in his final game for Atletico Madrid.
Real Madrid dropped points for the third time in seven games since Zinedine Zidane's return as they were held to a 0-0 draw away to Getafe in La Liga on Thursday, which harmed their neighbours' hopes of a top-four finish.
News of all that's transpired on and off the football field
Barcelona forward Ousmane Dembele scored twice and produced a mesmerising display to fire his side to a 5-1 win over Villarreal on Wednesday which stretched the champions' unbeaten run this season to 36 games with two remaining.
News of all that's transpired on and off the football field
News of all that's transpired on and off the football field
IMAGES from the La Liga matches played on Tuesday
Barcelona moved six points clear at the top of La Liga by easing to a 4-0 win at home to Deportivo La Coruna on Sunday with doubles from Luis Suarez and Paulinho ahead of next week's 'Clasico' against champions Real Madrid.
Barcelona teenager Ansu Fati scored twice to lead his side to a 2-1 win at home to Levante on Sunday, finding the net in a league game for the first time in more than four months and becoming the youngest player to net a La Liga double. Romelu Lukaku scored a quickfire second-half double to give Inter Milan a 2-0 win at Udinese on Sunday, ending their run of three successive 1-1 league draws.
La Liga champions Barcelona began the new campaign with a 3-0 win over Alaves on Saturday with the help of a spectacular under-the-wall free kick from Lionel Messi, who scored twice, and a curling shot from substitute Philippe Coutinho.
News of all that's transpired on and off the football field
Valverde said he was concerned about the team's away form after they were comprehensively beaten 2-0 by promoted Granada
News of all that's transpired on and off the football field.
News of all that transpired on and off the football field.
Champions Barcelona reclaimed top spot in La Liga on Sunday by overcoming a dogged Villarreal side to win 2-0 at home with goals from stalwart defender Gerard Pique and youngster Carles Alena taking them above Sevilla.
Cristiano Ronaldo helped Juventus continue their unbeaten start to the Serie A season with a comfortable 2-0 home victory over struggling SPAL on Saturday.
Lionel Messi dragged Barcelona back from two goals down by scoring twice to snatch a 2-2 draw at home to Valencia in a thrilling encounter.
Barcelona snapped a four-match winless run in La Liga with a 4-2 home victory over title rivals Sevilla on Saturday to reclaim top spot but the triumph was marred by talisman Lionel Messi fracturing his arm and being ruled out for three weeks.
La Liga leaders Barcelona handed Real Madrid more hope in the title race as they drew 0-0 at Athletic Bilbao on Sunday, only avoiding defeat thanks to some outstanding saves by Marc-Andre ter Stegen.
News of all that's transpired on and off the football field
News of all that's transpired on and off the football field
News of all that's transpired on and off the football field
Lionel Messi fittingly sealed Barcelona's 26th La Liga title on Saturday by coming off the bench to score the goal in a 1-0 win over Levante in front of a jubilant Nou Camp crowd, who celebrated a remarkable eighth league crown in 11 years.